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Buying guide

Why purity alone is not enough

Every seller in this market leads with a purity number, and buyers have learned to shop on it. But 99% answers only one of the four questions that decide whether a vial is what you paid for — and it is not the most important one.

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The gap

What a percentage actually asserts

An HPLC purity figure says: of what is in this sample, 99% is a single substance. Read that sentence again, because it never names the substance. Purity is a statement about homogeneity, not about identity.

A vial can be 99% pure and 100% wrong — the wrong compound, cleanly synthesised. It can also be the right compound at the right purity in the wrong amount, five milligrams sold as ten. And it can pass all three tests and still arrive degraded, because a certificate describes the batch at analysis, not the vial after transit.

Identity, quantity, condition. Three questions the headline number does not touch, each with its own check.

The full picture

Four questions, not one

What complete verification actually covers.

  1. 01

    Identity — is it the named compound?

    Answered by mass spectrometry, not chromatography. The found mass must match what the sequence predicts. This line outranks the purity line every single time.

    Reading the identity section
  2. 02

    Purity — how much of the sample is that compound?

    The famous number, valid only with a method and a chromatogram attached. Our floor is 99% by HPLC, stated per batch rather than per catalogue.

    When the number is invented
  3. 03

    Quantity — how many milligrams are really there?

    Underfilling is the quiet fraud: right compound, right purity, wrong amount, and every downstream calculation silently off. Net content belongs on the certificate too.

    Why the milligrams matter
  4. 04

    Condition — did it survive the journey?

    Peptides degrade with heat, light and time. Analysis-day numbers do not cover a fortnight in a hot van, which is what packing and transit standards exist for.

    Keeping it intact after arrival
The market effect

When one number does all the talking

Purity became the market’s shorthand because it compresses into a badge. Identity confirmation, net content and cold-chain handling resist compression, so they fell out of the conversation, and sellers learned to compete on the number that survived.

The result is purity inflation: claims drifting toward 99.9% and beyond, printed in fonts larger than the evidence behind them. Meanwhile the failures that actually burn buyers — wrong compound, short fill, cooked in transit — sit precisely in the questions the badge ignores.

Our advice compresses too: treat purity as an entry ticket, not a verdict. Below 99%, walk away; at 99%, start asking the other three questions.

The three silent failures
  • Right purity, wrong compoundClean synthesis of the wrong sequence passes every purity test ever run.
  • Right compound, short fillMilligrams are promised on the label and verified almost nowhere. Ask for net content.
  • Right vial, dead on arrivalDegradation en route is invisible on paper. Packing standards are part of quality, not logistics.
  • Right paper, wrong batchThe recycled-certificate trick — covered in full in the fake-COA guide.
Questions

About the number

Purity questions that deserve straight answers.

Is 99.9% meaningfully better than 99%?
For most research purposes the difference is marginal, and claims above 99.5% deserve more scepticism, not more trust — resolution and honesty both have limits.
What is the other 1%?
Typically water, residual salts from synthesis, and truncated sequence fragments. A good certificate characterises the main impurities rather than leaving them anonymous.
Can purity change after the certificate is issued?
Yes — that is the condition question. Heat, light and repeated freeze-thaw all erode it, which is why storage pages exist and why packing matters.
Why is your floor 99% and not higher?
Because 99% by HPLC is a standard we can hit and document on every batch, rather than a marketing number we could print on some. We would rather be held to a real floor.
Four questions

Ask all four, every time

Identity, purity, quantity, condition. Any supplier worth an order can answer all four for the specific batch you would receive. We can.

For laboratory and research use only. Not for human or animal consumption. Not a medicine and not a food supplement. Sold to persons aged 18 and over.

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