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Compound file

What is selank?

A synthetic peptide built from a fragment of an immune protein, studied in Russia as an anxiolytic. Like several compounds in this corner of the catalogue, the interesting part is as much about how the evidence is structured as about the molecule itself.

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Origin

Tuftsin, extended for stability

Tuftsin is a four-residue fragment of an antibody, known since the 1970s for its role in immune signalling. Selank takes that fragment and adds three residues to it, a modification intended to slow how quickly enzymes break it down.

That design tells you something about the research question. The point was never the immune role of tuftsin on its own; it was whether a stabilised version would persist long enough to study effects on the central nervous system.

Mechanism

What the studies actually measured

The published work looks at anxiety-related behaviour in animal models and, in a smaller set of studies, in people. Proposed mechanisms involve GABAergic signalling and expression of brain-derived neurotrophic factor, both measured indirectly.

Sample sizes in the human work are small and the studies come from a limited number of groups. That is the honest summary, and it is why we describe it as a compound studied in anxiety research rather than an anxiolytic.

At a glance
Base sequenceTuftsin fragment, extended
Length7 amino acids
OriginSynthetic, Russian research
Proposed targetsGABAergic signalling, BDNF expression
FormatsPeptide pen and nasal spray
Purity≥ 99% (HPLC)
Evidence baseAnimal models and small human studies
CategoryResearch use only

These are handling and identity facts. They carry no claim about results.

In practice

Why it appears as a nasal spray

Seven residues is short enough for the nasal route to be worth investigating, which is why selank shows up in that format alongside the pen. The mucosal route appears far more often in this research area than anywhere else in the catalogue, and chain length is the reason.

Which format suits your work depends on what you are comparing. Neither is presented here as better than the other.

What we supply

Selank in the catalogue

Purity is confirmed at 99% minimum before release; ask for the certificate matching your batch.

Frequently asked

About Selank

Four questions that come up in almost every enquiry.

Is selank an approved medicine?
Not in the EU. It has been used clinically in some jurisdictions under different regulatory systems, which is not the same as approval here and should not be read as one.
How does it differ from tuftsin?
Selank is tuftsin with three extra residues added to slow enzymatic breakdown. The parent fragment has its own immune-related literature that does not automatically transfer.
Pen or nasal spray?
Both routes appear in the literature. The spray removes sharps from the workflow; the pen gives a different exposure profile. Which fits depends on what your protocol is comparing.
Why is the human evidence described as limited?
Because the studies are small and come from a narrow set of groups. That is a statement about the structure of the evidence, not a judgement on the findings themselves.
Before you order

Ask for the batch number

We would rather describe a limited literature accurately than inflate it. What we can demonstrate is identity and purity, and that part is documented per batch.

For laboratory and research use only. Not for human or animal consumption. Not a medicine and not a food supplement. Sold to persons aged 18 and over.

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